CHEM 100 Foundations of Chemistry (4)
This course explores the foundational principles of chemistry within the context of contemporary topics in the chemical sciences and society. In addition to introducing the central models and theories of chemistry, the course develops a student’s skills in analytical reasoning and problem-solving. Successful completion prepares students with little or no previous background in chemistry to enroll in CHEM 120.
CHEM 101 General Chemistry I (Lab) (4)
Atoms, molecules, and ions; stoichiometry; reactions in aqueous solutions; gases; thermochemistry; atomic structure; electron configurations and the periodic table; chemical bonds; molecular structure; states of matter and intermolecular forces. Lecture, three hours; laboratory, three hours.
CHEM 102 General Chemistry II (Lab) (4)
Chemical kinetics; equilibrium; acids and bases; equilibrium of slightly soluble salts and complex ions; thermodynamics; electrochemistry; chemistry of representative elements; organic functional groups; polymers-both biochemical and man-made. Lecture, three hours; laboratory, three hours. Prerequisite: CHEM 101.
CHEM 103 Earth, Air, Water and Fire: An Introduction to Environmental Chemistry (Lab) (4)
An introduction to Environmental Chemistry. Both the natural environment and modern society run on innumerable chemical processes. This course examines the natural chemistry responsible for our environment and some of the anthropomorphic processes that have the potential to disrupt it. The course also examines how understanding this chemistry does or does not inform public perception and policy. Lecture, three hours; laboratory, three hours. Prerequisite: CHEM 101.
CHEM 108 Chemistry and Art (Lab) (4)
A study of the chemistry underlying some topics that are of particular interest to artists. Topics may include paper making, pigments and binders, photography, glass making and coloring, metal casting, and printmaking. The course is designed for the general student and meets the laboratory science requirement. Lecture, three hours; laboratory, three hours.
CHEM 110 The Science of Food and Cooking (4)
An introduction to the science of food and food preparation. Students learn the scientific method through reading and modifying cooking recipes. Recent literature in the field of gastronomy as well as controversies about such issues as low-carbohydrate diets and genetically modified foods are considered. The course is designed for the general student and meets the laboratory science requirement. Lecture, three hours; laboratory, three hours. Open only to new first-year students.
CHEM 112 Chemistry of Art and Artifacts (4)
This course addresses both of these intersections between science and the arts by considering the role of chemistry in the production and interpretation of art and artifacts from theoretical and practical perspectives. The course also examines the application of chemistry to art conservation and archaeology.
CHEM 120 General Chemistry (Lab) (4)
A survey of the basic chemical principles and theories, with emphasis on applying these concepts to chemically related fields such as environmental science and biological chemistry. Topics considered include atomistic and molecular structure, kinetics, thermodynamics, and chemical equilibrium. The course’s laboratory portion emphasizes the collection and interpretation of data, as well as the formation and testing of hypotheses. Lecture, three hours; laboratory, three hours. Prerequisite: CHEM 100 or placement.
CHEM 150 Advanced General Chemistry (Lab) (4)
An introduction to fundamental chemical concepts with an emphasis on understanding and analytical reasoning. The course focuses on the molecular basis of matter and its transformation as well as the role of chemistry in the broader scientific and societal enterprise. The laboratory portion of the course emphasizes the collection and interpretation of empirical data. This course is intended for students with a significant background and interest in the chemical sciences. Open only to new first-year students.
CHEM 201 Organic Chemistry I (Lab) (4)
A study of the nomenclature and the properties of the most important classes of organic compounds with an emphasis on concepts relating molecular structure and properties. Stereochemistry, functional group transformations and reaction mechanisms are studied in depth. Lecture, three hours; laboratory, three hours. Prerequisite: CHEM 102 or CHEM 111 or CHEM 120 or CHEM 150.
CHEM 202 Organic Chemistry II (Lab) (4)
A continuation of CHEM 201. A portion of the course is devoted to the study of important classes of biochemical compounds. Lecture, three hours; laboratory, three hours. Prerequisite: CHEM 201.
CHEM 211 Chemical Methods of Environmental Analysis (Lab) (4)
This course examines the interactions among chemical, physical, geological, and biological processes that define the natural world. Fundamental chemical processes occurring within natural waters, soils, and the atmosphere are emphasized with consideration of anthropogenic activities. Specific topics include the origin and evolution of Earth, atmospheric chemistry, organic and inorganic components of soil and water, chemical weathering, and chemical fate and transport. Environmental problems such as acid deposition, climate change, loss of atmospheric ozone, pollution, and water treatment are also discussed. Laboratory course. Prerequisite: CHEM 102 or CHEM 111 or CHEM 120 or CHEM 150.
CHEM 301 Chemistry Seminar for Juniors (2)
A series of lectures by faculty, students, and invited speakers. Junior majors will give talks on topics agreed upon with a faculty mentor. Talks describing student research are encouraged. Open only to juniors pursuing majors in chemistry.
CHEM 306 Biochemistry (4)
Introduction to the major areas of biochemistry. Lecture, three hours. Prerequisite: BIOL 233 and CHEM 201.
CHEM 307 Mechanistic Biochemistry (Lab) (4)
An examination of all aspects of protein science, including protein biosynthesis, protein structure, and the mechanisms of enzyme catalysis, with particular emphasis on the biochemistry of enzyme catalysis. Lecture, three hours; laboratory, three and one-half hours. Prerequisite: CHEM 202.
CHEM 308 Inorganic Chemistry (Lab) (4)
A survey of the inorganic and organometallic chemistry of the elements. Lecture, three hours; laboratory, three hours. Prerequisite: CHEM 201.
CHEM 311 Instrumental Analysis (Lab) (4)
An introduction to the theory and practice of the fundamental principles of chemical analysis and the use of chemical instrumentation in research. Course topics include solution equilibria in acid-base and complex-ion systems; electrochemical fundamentals and electroanalytical techniques; spectrophotometric and spectroscopic methods; and chromatographic and separation methods. Lecture, three hours; laboratory, three hours. Prerequisite: CHEM 211.
CHEM 316 Biochemistry of Metabolism and Molecular Biology (Lab) (4)
A study of the biochemical reactions of eukaryotic cellular metabolism and bioenergetics, focusing on enzyme regulation and function, protein structure, nucleic acid structure and function, and selected topics in molecular biology and physiological biochemistry. Prior coursework in cell/molecular biology is recommended. Laboratory course. Prerequisite: BIOL 233 and CHEM 202.
CHEM 352 Thermodynamics and Kinetics (Lab) (4)
An introduction to thermodynamics and kinetics. Not open to students who have received credit for CHEM 322. Lecture, three hours; laboratory, three hours. Prerequisite: CHEM 201 and MATH 102. Prerequisite or Corequisite: PHYS 101 or PHYS 103.
CHEM 401 Chemistry Seminar for Seniors (2)
A series of lectures by faculty, students, and invited speakers. Senior majors will give talks on topics agreed upon with a faculty mentor. Talks describing student research are encouraged. Open only to seniors pursuing majors in chemistry.
CHEM 405 Organic Synthesis (4)
A comprehensive study of modern organic reactions and their application to the synthesis of biologically-active natural products. Prerequisite: CHEM 202.
CHEM 408 Advanced Topics in Inorganic Chemistry (4)
Selected topics in modern inorganic chemistry, such as bioinorganic chemistry, materials chemistry, and organometallic chemistry. The course surveys relevant primary literature. Topics may vary from year to year, and the course may be repeated for credit, depending upon the topic. Lecture, three hours. Prerequisite: CHEM 308.
CHEM 411 Geochemistry of Natural Waters (4)
A quantitative examination of the chemical processes that occur in aquatic environments, including precipitation, gas exchange, acid-base, redox, complexation, and adsorption reactions. Emphasis is on equilibrium and steady-state calculations as a tool for understanding the distribution and fate of inorganic chemical species in natural waters. Examples and case studies are used to address a variety of water types (e.g., lakes, oceans, rivers, estuaries, groundwaters, and wastewaters), pollutant fate, and geochemistry. CHEM 311 and CHEM 352 recommended. Prerequisite: CHEM 102 or CHEM 111 or CHEM 150. Prerequisite or Corequisite: CHEM 120.
CHEM 412 Advanced Environmental Geochemistry (4)
An examination of the chemical principles that determine how natural systems work and how anthropogenic activities can have an impact on the function of these systems. Topics include both fundamental chemical principles and case studies of particular environmental systems. Lecture, three hours. Prerequisite: CHEM 102 or CHEM 111 or CHEM 120 or CHEM 150.
CHEM 415 Mechanistic Enzymology (4)
An examination, from an organic mechanistic perspective, of traditional and non-traditional uses of coenzymes in enzymatic catalysis. Particular emphasis is placed on the experimental methods used to provide evidence for proposed mechanistic pathways such as the use of isotopic labels and fluorinated substrate analogues as well as assorted spectroscopic techniques. Additional topics include the biosynthesis of various classes of secondary metabolites such as polyketides, terprenes, and deoxysugars. Prerequisite: CHEM 202.
CHEM 417 Advanced Biochemistry (4)
An exploration of contemporary issues in biochemistry based largely on primary literature. Topics such as the biosynthesis and mode of action of antibiotics, protein engineering, signal transduction, chemical carcinogenesis, and isotope effects in enzyme kinetics will be addressed in detail. Prerequisite: BIOL 306 or BIOL 307 or CHEM 316 or CHEM 306 or CHEM 307.
CHEM 418 Structural Methods (4)
This course examines the theory and praxis of molecular and macromolecular structure determination via spectroscopic and physical methods. Lecture, three hours. Prerequisite: CHEM 202.
CHEM 422 Quantum Chemistry and Spectroscopy (4)
An introduction to quantum mechanics in chemistry and spectroscopy. Lecture, three hours. Prerequisite: CHEM 201 and MATH 102 and (PHYS 102 or PHYS 104).
CHEM 424 Topics in Physical Chemistry (4)
Prerequisite: CHEM 352 and CHEM 422.
CHEM 425 Drug Design and Development (4)
An examination of the fundamental chemical aspects associated with the process of discovering new drugs. Both combinatorial and rational drug design methodologies are addressed. Emphasis is on the application of various structure-based and mechanism-based strategies for drug optimization. Additional topics include pharmacokinetics (how drugs move within the body), metabolism of drugs, and pharmacodynamics (effect of drugs and their molecular mechanism of action). Prerequisite: CHEM 202.
CHEM 428 Advanced Topics in Analytical Chemistry (4)
This course covers the theory and practice of special methods and recent advances in analytical chemistry. Prerequisite: CHEM 311.
CHEM 444 Research/Independent Study (2 or 4)
Qualified juniors and seniors may do research or independent study under the supervision of a member of the chemistry department.
CHEM 494 Mentored Research in Chemistry (2 or 4)
Students engage in original research in chemistry under the mentorship of a faculty member. Students apply and integrate knowledge from their coursework while learning both specific laboratory techniques and practical problem-solving skills. Discussion of proper laboratory record-keeping, responsible conduct of research, presentation of research results, and laboratory safety are also emphasized. Repeatable for credit.